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3,4-methylenedioxy-methamphetamine (MDMA) is a synthetic drug that alters mood and perception (awareness of surrounding objects and conditions). It is chemically similar to both stimulants and hallucinogens, producing feelings of increased energy, pleasure, emotional warmth, and distorted sensory and time perception.
MDMA was initially popular in the nightclub scene and at all-night dance parties (“raves”), but the drug now affects a broader range of people who more commonly call the drug Ecstasy or Molly.
3,4-Methylenedioxymethamphetamine, commonly known as ecstasy, is a psychoactive drug primarily used as a recreational drug. The desired effects include altered sensations and increased energy, empathy, and pleasure. When taken by mouth, effects begin after 30–45 minutes and last 3–6 hours. Wikipedia
Onset of action: 30–45 minutes (by mouth)
Duration of action: 4–6 hours
Metabolism: Liver, CYP450 extensively involved, including CYP2D6
Elimination half-life: (R)-MDMA: 5.8 ± 2.2 hours (variable); (S)-MDMA: 3.6 ± 0.9 hours (variable)
Metabolites: MDA, HMMA, HMA, DHA, MDP2P, MDOH..
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is a common recreational drug. It is also known as Molly or Ecstasy, and to a lesser extent, Mandy or Adam. MDMA is also beginning Phase 3 trials with the US FDA for the treatment of PTSD.
“MDMA’s risk profile is low enough to justify further explorations in clinical trial settings. However, this only applies to carefully designed research contexts with screened adult subjects, and does not apply to any other use of MDMA.
Molly vs Ecstasy vs MDMA
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MDMA is the official chemical name for the pure chemical compound – in an ideal world, Molly would be 100% pure MDMA. Molly is a street name for MDMA in powder form, often contained in clear capsules. “Molly” doesn’t mean pure. Ecstasy is a street name for MDMA in pill/tablet form.
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Caution: Drugs sold as MDMA, Molly or Ecstasy are often impure. 87% of “Molly” analyzed by the DEA between 2009 and 2013 contained 0% MDMA, instead mostly containing “bath salts.”
MDMA is the official scientific name for this drug. “Molly” and “ecstasy” are both commonly-used slang terms.
However, since MDMA is currently illegal and therefore unregulated, anything sold as “molly” or “ecstasy” could range from being pure MDMA, to being cut with other drugs, to containing no MDMA at all. The molly market is one of the most adulterated illicit drug markets, meaning it often is cut with other substances. (See this of what ecstasy or molly may contain.).